During a recent project where I was creating a SharePoint feature I had the need to clear the browser cache before starting a new debug session. The feature was all JavaScript and I wanted to be sure I was getting the latest version. So, I added this command to the post build event.
InetCpl.cpl,ClearMyTracksByProcess 8
I have also used this in trouble shooting browser issues with clients, the easiest way to know for sure they have cleared their browser cache.